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Structural Organization of the Pre-mRNA Splicing Commitment: A Hypothesis

✍ Scribed by Ivo Melčák; Ivan Raška


Book ID
115633808
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
108 KB
Volume
117
Category
Article
ISSN
1047-8477

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Nuclear pre-mRNAs must be precisely processed to give rise to mature cytoplasmic mRNAs. This maturation process, known as splicing, involves excision of intron sequences and ligation of the exon sequences. One of the major problems in understanding this process is how splice sites, the sequences whi