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Structure and function of nucleases in DNA repair: shape, grip and blade of the DNA scissors

✍ Scribed by Nishino, Tatsuya; Morikawa, Kosuke

Book ID
110067258
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
763 KB
Volume
21
Category
Article
ISSN
0950-9232

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## Abstract DNA mismatch repair (MMR) is one of the several enzyme systems involved in DNA homeostasis. DNA MMR is involved in the repair of specific types of errors that occur during new DNA synthesis; loss of this system leads to an accelerated accumulation of potential mutations, and predisposes