The OGG1 gene of Saccharomyces cerevisiae encodes a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine (8-OxoG). When compared to wild-type, ogg1 mutants show an increase in the frequency of GC to TA transversions, indicating a role for Ogg1 in the repair of 8-OxoG. Here we report an increased fr
Role of yeast Rth1 nuclease and its homologs in mutation avoidance, DNA repair, and DNA replication
β Scribed by Robert E. Johnson; Gopala K. Kovvali; Louise Prakash; S. Prakash
- Publisher
- Springer-Verlag
- Year
- 1998
- Tongue
- English
- Weight
- 182 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0172-8083
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