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Structure-activity relationships of met5- and leus-enkephalin analogues

โœ Scribed by M. J. Quinn; F. J. Laska; M. R. Fennessy


Book ID
108932862
Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
354 KB
Volume
6
Category
Article
ISSN
0305-1870

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Structureโ€“activity relationships of usti
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Four novel ustiloxin D analogues were synthesized focusing on the size of the macrocyclic core, the stereochemistry at the bridgehead ether, and the enantiomer of ustiloxin D. All four were subjected to biological evaluation testing the inhibition of tubulin polymerization. Only 2,2-dimethyl-ustilox