Four novel ustiloxin D analogues were synthesized focusing on the size of the macrocyclic core, the stereochemistry at the bridgehead ether, and the enantiomer of ustiloxin D. All four were subjected to biological evaluation testing the inhibition of tubulin polymerization. Only 2,2-dimethyl-ustilox
Structure-activity relationships of raphanusanins and their analogues
✍ Scribed by Masako Sakoda; Kenji Usui; Kozo Ishizuka; Nobuyuki Harada; Hiroshi Ono; Hisashi Uda; Koji Hasegawa
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 256 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0031-9422
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
AbstractÐOpioid binding anities were assessed for a series of cyclazocine analogues where the prototypic 8-OH substituent of cyclazocine was replaced by amino and substituted-amino groups. For m and k opioid receptors, secondary amine derivatives having the (2R,6R,11R)-con®guration had the highest a
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v