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Structure activity relationship of epoxides: Different mutagenicity of the two diastereoisomeric 3-bromo-1,2-epoxycyclohexanes

✍ Scribed by G. Bellucci; A. Lippi; F. Marioni; L. Citti; P.G. Gervasi; G. Turchi


Book ID
113136741
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
751 KB
Volume
51
Category
Article
ISSN
0009-2797

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Cover Picture: Structure–Activity Relati
✍ Sylvain Petit; Yann Duroc; Valéry Larue; Carmela Giglione; Carole Léon; Coralie 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 694 KB

## Abstract **The cover picture shows** a “reverse” indole derivative in complex with __Bacillus stearothermophilus__ peptide deformylase (PDF). This compound was selected from a structure–activity relationship study as a potent inhibitor of bacterial PDFs and shows antibacterial activity toward __