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Structural requirements for the biological activity of enterostatin

✍ Scribed by L. Lin; S. Okada; D.A. York; G.A. Bray

Book ID
119142915
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
569 KB
Volume
15
Category
Article
ISSN
0196-9781

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A stepwise degradation of the oligosaccharide part of moenomycin A (2) was performed. The degradation products were assayed for antibiotic activity both in vivo and in an E.coli cell-free system. Units E, F, G, H, and I have been found -to be essential for full biological (in vitro) activity. \_-It