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Structural Relationship and Binding Mechanisms of Five Flavonoids with Bovine Serum Albumin

✍ Scribed by Liu, E-Hu; Qi, Lian-Wen; Li, Ping

Book ID
120311460
Publisher
Molecular Diversity Preservation International
Year
2010
Tongue
English
Weight
386 KB
Volume
15
Category
Article
ISSN
1420-3049

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The binding constants and the number of binding sites for the binding of 11 sulfonamide and seven penicillin derivatives to bovine serum albumin were determined using a fluorescence probe method. The results demonstrate that these drugs bind to hydrophobic sites on the serum albumin. The binding aff