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Structural investigation of the capsular polysaccharide of Klebsiella serotype K67

โœ Scribed by Guy G.S. Dutton; D.Nedra Karunaratne


Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
702 KB
Volume
119
Category
Article
ISSN
0008-6215

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โœฆ Synopsis


The determination of the structure of the capsular polysaccharide from Klebsiella K67 involved the use of methylation, periodate oxidation, partial hydrolysis, and &elimination.

The nature of the anomeric linkages was established by using 'H-and '"C-n.m.r. spectroscopy, and was further confirmed by chromic acid oxidation of the fully acetylated polysaccharide.

The polysaccharide was found to have the heptasaccharide repeating unit shown. A structure having a branched sidechain is unique in this series of capsular polysaccharides.


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