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Structural elucidation of the capsular polysaccharide of Escherichia coli serotype K101 by a high resolution NMR spectroscopy

✍ Scribed by M. Ruth Grue; Haralambos Parolis; Lesley A.S. Parolis

Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 457 KB
Volume: 246
Category: Article
ISSN: 0008-6215
DOI: 10.1016/0008-6215(93)84040-d

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✦ Synopsis

The primary structure of the acidic capsular antigen of Escherichia coli 020:K101 was shown by glycose analysis, methylation analysis, and one-and two-dimensional 'H and "C NMR spectroscopy to be composed of repeating branched-tetrasaccharide units having the structure:

--f 3)-fi-o-GalpNAc-(1 --f 4)-p-D-GkpA-(1 + 3)-@o-Gal&l-3

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