✦ LIBER ✦

Structural elucidation of the novel type VII group B Streptococcus capsular polysaccharide by high resolution NMR spectroscopy

✍ Scribed by Grigorij Kogan; Jean-Robert Brisson; Dennis L. Kasper; Christina von Hunolstein; Graziella Orefici; Harold J. Jennings

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 488 KB
Volume: 277
Category: Article
ISSN: 0008-6215
DOI: 10.1016/0008-6215(95)00195-y

No coin nor oath required. For personal study only.

✦ Synopsis

The type VII capsular polysaccharide isolated from the newly discovered group B Streptococcus (GBS) strain contains o-glucose, D-galactose, N-acetyl-D-glucosamine and N-acetylneuraminic acid in the molar ratio 2:2:1:1. High-resolution one-and two-dimensional (ID and 2D) ~H and J3C NMR spectroscopy of the native and desialylated polysaccharides showed the type VII GBS capsular polysaccharide to contain the following branched hexasaccharide repeating unit:

Despite extensive structural similarity with the previously described GBS polysaccharides, the type VII polysaccharide showed no cross-reaction with the heterologous antisera.

📜 SIMILAR VOLUMES

Structural elucidation of the capsular p

Structural elucidation of the capsular polysaccharide of Escherichia coli serotype K101 by a high resolution NMR spectroscopy

✍ M. Ruth Grue; Haralambos Parolis; Lesley A.S. Parolis 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 457 KB

The primary structure of the acidic capsular antigen of Escherichia coli 020:K101 was shown by glycose analysis, methylation analysis, and one-and two-dimensional 'H and "C NMR spectroscopy to be composed of repeating branched-tetrasaccharide units having the structure: --f 3)-fi-o-GalpNAc-(1 --f 4

Structural elucidation of the capsular p

Structural elucidation of the capsular polysaccharide expressed by Escherichia coli O20:K83:H26 by high resolution NMR spectroscopy

✍ Darryl V. Whittaker; Lesley A.S. Parolis; Haralambos Parolis 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 640 KB