The structure of the Pneumococcus type 19A (57) capsular polysaccharide has been reinvestigated by using methylation analysis and n.m.r. spectroscopy. It is composed of residues of 2-acetamido-2-deoxy-D-mannose, D-glUCOSe, L-rhamnose, and phosphate in the molar ratios of 1:l: 1:l. The polysaccharide
Structural determination of the capsular polysaccharide of Streptococcus pneumoniae type 18C (56)
β Scribed by Czeslaw Lugowski; Harold J. Jennings
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 748 KB
- Volume
- 131
- Category
- Article
- ISSN
- 0008-6215
No coin nor oath required. For personal study only.
β¦ Synopsis
The specific capsular polysaccharide of Streptococcus pneumoniae type 18C (56) contains D-glucose, D-galactose, L-rhamnose, and glycerol residues, and phosphate and O-acetyl groups in the molar ratios of 3:1:1:1:1:1. Accumulated data from methylation analyses of the native and the specifically degraded, native polysaccharide indicated that it is composed of the repeating unit shown; it also contains O-acetyl groups, of undetermined location, in the molar ratio to L-rhamnose of 1:1. (formula; see text).
π SIMILAR VOLUMES
The structure of the capsular polysaccharide (S5) elaborated by Streptococcus pneumoniae type 5 has been investigated by using n.m.r. spectroscopy, methylation analysis, and various specific degradations. It is concluded that the polysaccharide is composed of pentasaccharide repeating-units having t
The capsular polysaccharide from Streptococcus pneumoniae Type 23 (S-23) was found to contain D-galactose, D-glucose, L-rhamnose, glycerol, and phosphorus in the ratios of 1: 1: 2:0.6: 1. Methylation analysis provided information about the linkages of the different sugar units. The sequence of the d
The structure of the capsular polysaccharide from Streptococcus pneumoniae type 2 has been reinvestigated, specific degradations and n.m.r. spectroscopy being the main methods used. It is concluded that the polysaccharide is composed of hexasaccharide repeating-units having the following structure,