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Structural Basis of HIV-1 and HIV-2 Protease Inhibition by a Monoclonal Antibody

✍ Scribed by Pavlina Rezacova; Julien Lescar; Jiri Brynda; Milan Fabry; Magda Horejsi; Juraj Sedlacek; Graham A. Bentley

Book ID
114328977
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
659 KB
Volume
9
Category
Article
ISSN
0969-2126

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Inhibition of HIV protease by monoclonal
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✍ P. Rezacova; J. Brynda; M. Fabry; M. Horejsi; R. Stouracova; J. Lescar; V. Chita πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 272 KB

## Abstract The protease of HIV plays a critical role in the maturation of the infectious particles of the virus. The enzyme has therefore been extensively studied with the objective of developing therapeutics that inhibit viral proliferation. We have produced monoclonal antibodies specific for the