Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody
✍ Scribed by Julien Lescar; Jiri Brynda; Graham A. Bentley; Marie-Madeleine Riottot; Véronique Chitarra; Pavlina Rezacova; Renata Stouracova; Milan Fabry; Magda Horejsi; Juraj Sedlacek
- Book ID
- 111753554
- Publisher
- Cold Spring Harbor Laboratory Press
- Year
- 2008
- Tongue
- English
- Weight
- 78 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0961-8368
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The protease of HIV plays a critical role in the maturation of the infectious particles of the virus. The enzyme has therefore been extensively studied with the objective of developing therapeutics that inhibit viral proliferation. We have produced monoclonal antibodies specific for the
HIV-1 and HIV-2 are co-endemic in certain geographic areas. HIV-2 is more weakly pathogenic than HIV-1, and progression to AIDS occurs less frequently and over a longer period of time. Recent epidemiologic studies suggest that individuals infected with HIV-2 have a lower risk of HIV-1 infection. Bot