𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Structural Basis for Inhibition of Histamine N-Methyltransferase by Diverse Drugs

✍ Scribed by John R. Horton; Ken Sawada; Masahiro Nishibori; Xiaodong Cheng


Book ID
116662418
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
566 KB
Volume
353
Category
Article
ISSN
0022-2836

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Stereoselective inhibition by chloroquin
✍ P. Donatelli; G. Marchi; G. M. Pacifici; L. Giuliani; L. L. Gustafsson πŸ“‚ Article πŸ“… 1994 πŸ› Springer 🌐 English βš– 421 KB

This study was designed to determine whether both enantiomers of chloroquine inhibit histamine N-methyltransferase. The mean estimates of ICs0 for the d-and/-enantiomers of chloroquine were 4.9 and 17.8 ~tM (liver), respectively and 6.9 and 21.6 ~tM (brain), respectively. K i estimates were signific