𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Brain histamine N-methyltransferase purification, mechanism of action, and inhibition by drugs

✍ Scribed by A. Thithapandha; V.H. Cohn

Book ID
115773977
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
947 KB
Volume
27
Category
Article
ISSN
0006-2952

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Stereoselective inhibition by chloroquin
Stereoselective inhibition by chloroquine of histamine N-methyltransferase in the human liver and brain
✍ P. Donatelli; G. Marchi; G. M. Pacifici; L. Giuliani; L. L. Gustafsson πŸ“‚ Article πŸ“… 1994 πŸ› Springer 🌐 English βš– 421 KB

This study was designed to determine whether both enantiomers of chloroquine inhibit histamine N-methyltransferase. The mean estimates of ICs0 for the d-and/-enantiomers of chloroquine were 4.9 and 17.8 ~tM (liver), respectively and 6.9 and 21.6 ~tM (brain), respectively. K i estimates were signific