The mammalian centromere is a multifunctional chromosomal domain with a complexity that is reflected in its higher order structure, DNA sequence organization and protein composition. The centromere plays a major role during cell division where it functions as the site for the integration of the chro
Structural analysis of a yeast centromere
β Scribed by Kerry Bloom; Alison Hill; Elaine Yeh
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 685 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0265-9247
No coin nor oath required. For personal study only.
β¦ Synopsis
reaffirmed, but, in addition, it was recommended that linkages to organizations of social scientists, engineers and medical scientists should be forged. Some of the proposals are for more of the same, where the 'same' under reference is to something that is known to be effective and to work well. These include interdisciplinary programs on global problems, or science and science education in the Third World. Others are for taking new directions, in science communication, in bringing in youth and encouraging equitable sex representation, perhaps by opening membership of ICSU to individuals. It was also recommended to diversify the sources of income, from governments, industries and foundations, including the possible establishment of an ICSU Foundation, but none of this is to be at the expense of ICSU's non-political nature.
This heavy agenda now falls to the lot of a follow-up group to massage, to put into priority order and to incorporate into a strategic plan for future development. Chaired by Walter A. Rosenblith, ICSU Vice-president and Foreign Secretary of the U.S. National Academy of Sciences, the group has everyone's best wishes. Goodwill towards ICSU is one commodity that is not in short
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## Abstract A procedure to stain the centromeric region of chromosomes for dual beam flow cytometric analysis is described. Serum from a CREST (Scleroderma syndrome) patient presenting a high titer of anticentromeric antibodies was chosen on the basis of specificity of labeling of cells on slides.
CHO chromosomes, prepared for fluorescence microscopy, or for scanning electron microscopy, sometimes show a splitting of the centromere proper into two sister centromeres, with a space between them, while the sister chromatids are joined in the most proximal regions of the chromosome arms. It is su