The mammalian centromere is a multifunctional chromosomal domain with a complexity that is reflected in its higher order structure, DNA sequence organization and protein composition. The centromere plays a major role during cell division where it functions as the site for the integration of the chro
THE STRUCTURE OF THE CENTROMERIC REGION OF CHO CHROMOSOMES
โ Scribed by A.T SUMNER
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 191 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1065-6995
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โฆ Synopsis
CHO chromosomes, prepared for fluorescence microscopy, or for scanning electron microscopy, sometimes show a splitting of the centromere proper into two sister centromeres, with a space between them, while the sister chromatids are joined in the most proximal regions of the chromosome arms. It is suggested that this might represent the final stage of chromatid splitting before the anaphase separation of chromatids.
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