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Structural alterations of the BCL-6 gene in B cell lymphoma

โœ Scribed by R. Dalla-Favera; B.H. Ye; A. Migliazza; S.R. Chaganti; W. Chang; C.-C. Chang; J. Zhang; G. Cattoretti; H. Niu; K. Offit

Book ID
113253755
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
97 KB
Volume
84
Category
Article
ISSN
0165-4608

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## Abstract ## BACKGROUND In Western populations, rearrangement of the __BCL__โ€6 gene can be identified in 20โ€“40% of patients with diffuse large Bโ€cell lymphoma (DLBCL). Analysis of the __BCL__โ€6 gene has revealed the presence of point mutations or small deletions in 70% of DLBCL tumors; however,

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