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Structural alterations of the FAS gene in cutaneous T-cell lymphoma (CTCL)

✍ Scribed by Jianqiang Wu; Jawed Siddiqui; Minakshi Nihal; Eric C. Vonderheid; Gary S. Wood

Book ID
116178760
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
735 KB
Volume
508
Category
Article
ISSN
0003-9861

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## Background: Fas (cd95; apo-1) is a transmembrane protein that mediates apoptosis upon cross-linking with fas-ligand (fas-l). interaction of fas-l expressed by cytotoxic t cells with fas-expressing tumour cells plays an important part in antitumour immune responses. ## Objectives: We aimed to i