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Striatal plasticity at the network level. Focus on adenosine A2A and D2 interactions in models of Parkinson's Disease

✍ Scribed by S Tanganelli; K Sandager Nielsen; L Ferraro; T Antonelli; J Kehr; R Franco; S Ferré; L.F Agnati; K Fuxe; J Scheel-Krüger


Book ID
116819965
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
264 KB
Volume
10
Category
Article
ISSN
1353-8020

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✍ Sylvie Chalon; Patrick Emond; Sylvie Bodard; Marie-Paule Vilar; Cynthia Thiercel 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 539 KB

The time course of the loss in presynaptic dopamine transporters (DAT) and of the increase in postsynaptic dopamine D2 receptors (D2R) was studied in a rat model of Parkinson's disease. For this, in vitro autoradiographic experiments were performed in the striatum using (E)-N-(3-iodoprop-2-enyl)-2be