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Stress, glucocorticoids and absences in a genetic epilepsy model

✍ Scribed by Elena A. Tolmacheva; Melly S. Oitzl; Gilles van Luijtelaar


Book ID
116983357
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
303 KB
Volume
61
Category
Article
ISSN
0018-506X

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Involvement of nitric oxide (NO) in the regulation of the epileptic activity was studied in WAG/Rij rats, a genetic model of absence epilepsy. I.c.v. administration of NO donors: S-nitroso-Nacetylpenicillamine (SNAP, 0.5 and 5 pg), 3-morpholino-sydnonimine (SIN-1, 0.5 and 5 pg) or sodium nitroprussi