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Brain uptake of diazepam and phenytoin in a genetic animal model of absence epilepsy

✍ Scribed by Joseph A Nicolazzo; Jessica A Steuten; Susan A Charman; Nerida Taylor; Philip J Davies; Steven Petrou


Book ID
108940682
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
175 KB
Volume
37
Category
Article
ISSN
0305-1870

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## Abstract We suggest that a dysregulation of energy metabolism in the brain of genetic absence epilepsy rats from Strasbourg (GAERS) could create a specific cerebral environment that would favor the expression of spike‐and‐wave discharges (SWD) in the thalamocortical loop, largely dependent on gl