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๐ SIMILAR VOLUMES
## Introduction Guanadrel s u l f a t e (Hylorel@) (4) i s an a n t i h y p e r t e n s i v e (2-7) drug o f demonstrated c l i n i c a l u t i l i t y . We prepared r a d i o a c t i v e forms o f t h i s drug f o r \*Guanadrel s u l f a t e i s t h e USAN name f o r (~,4-dioxaspiro[4.5]dec-2-ylm
A method for determining low levels of tritium radioactivity in biological samples by means of a one-step combustion operation and a low background counting tube was described by Koenig and Brattghrd in 1963 (1). This technique has been applied in several cases in which low sample activity prevented
## Abstract Nโ[4โ]2โ(5โChloro โ2โmethoxybenzamido) ethyl phenylsulfonyl Nโฒ โcyclohexylurea, IXc, or glyburide, has been labeled with tritium and carbonโ 14. The tritium label is located in the Cโ3 position of the 5โchloro โ2โmethoxybenzoyl portion of the molecule, while the carbonโ14 label is incor
Timefurone (I), a methyl thioether analogue of khel lin (2), was labeled with tritium at the C-2 position and with carbon-14 at the C-5 position for conducting in uivo biotransformation studies with I . Tritium labeled I was prepared by lithiating and tritiating a silyllated derivative of khellinone