Strategy for the chiral separation of non-acidic pharmaceuticals using capillary electrochromatography
✍ Scribed by Debby Mangelings; Jérôme Discry; Mohamed Maftouh; D. Luc Massart; Yvan Vander Heyden
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 167 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0173-0835
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## Abstract A generic strategy for the chiral separation of non‐acidic pharmaceuticals was updated to complete an approach defined earlier. The selected chiral stationary phases are all polysaccharide selectors, chlorinated, and non‐chlorinated, namely Lux^®^ Amylose 2, Chiralcel^®^ OD‐RH, Lux^®^ C
## Abstract This paper deals with the chiral separation of hydroxy acids using diallyl‐dimethylammonium chloride as a positive charge‐providing agent in the continuous bed. The chiral continuous bed was prepared by __in situ__ copolymerization of monomers, including an L‐4‐hydroxyproline derivative