Strategies for the de novo design of proteins
β Scribed by M. Mutter; K.-H. Altmann; G. Tuchscherer; S. Vuilleumier
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 847 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4020
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract __De novo__ design programs such as LEGEND, LUDI, and LeapFrog can identify novel structures that are predicted to fit the active site of a target protein. However, in the conventional __de novo__ design strategy, the output structures obtained from the programs can be problematic with