Recent advances in de novo design strate
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Teruki Honma
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Article
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2003
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John Wiley and Sons
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English
โ 772 KB
## Abstract __De novo__ design programs such as LEGEND, LUDI, and LeapFrog can identify novel structures that are predicted to fit the active site of a target protein. However, in the conventional __de novo__ design strategy, the output structures obtained from the programs can be problematic with