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Stimulatory effect of cyclodextrins on the production of lankacidin-group antibiotics byStreptomycesspecies

✍ Scribed by Hidekazu Sawada; Takashi Suzuki; Shun-ichi Akiyama; Yoshio Nakao

Publisher
Springer
Year
1987
Tongue
English
Weight
407 KB
Volume
26
Category
Article
ISSN
1432-0614

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πŸ“œ SIMILAR VOLUMES

Mechanism of the stimulatory effect of c
Mechanism of the stimulatory effect of cyclodextrins on lankacidin-producingStreptomyces
✍ Hidekazu Sawada; Takashi Suzuki; Shun-ichi Akiyama; Yoshio Nakao πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 450 KB

Gel-filtration analysis of a mixture of cyclodextrin (CyD) and lankacidin C showed that fl-CyD had strong, ?'-CyD weak and a -C y D no affinity for lankacidin C. Lankacidin C production activity, which was assayed by measuring the incorporation of L-[methyl-14C-]methionine into the lankacidin molecu

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## Abstract Adding 10–50 mg/l of synthetic unsaturated lipids or natural oils to the nutrient media during antibiotic fermentation increases the yield of antibiotics 10 to 20 fold. Very high concentrations of lipids are sometimes inhibitory to antibiotic production.