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Stimulation of transcriptional expression of human UDP-glucuronosyltransferase 1A1 by dexamethasone

✍ Scribed by Masanobu Kanou; Toru Usui; Hisao Ueyama; Hiroshi Sato; Iwao Ohkubo; Takaharu Mizutani

Book ID
111600905
Publisher
Springer
Year
2004
Tongue
English
Weight
216 KB
Volume
31
Category
Article
ISSN
0301-4851

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Modulation of UDP-glucuronosyltransferas
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✍ Cornelia M. Smith; Stephanie R. Faucette; Hongbing Wang; Edward L. LeCluyse πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 477 KB

## Abstract The primary objective of this study was to evaluate the modulation of UGT1A1 expression in human hepatocytes using prototypical CYP450 inducers. A bank of 16 human livers was utilized to obtain an estimate of the range of UGT1A1 protein expression and catalytic activity. Concentration‐d