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Induction of Human UDP-Glucuronosyltransferase UGT1A1 by Flavonoids---Structural Requirements

✍ Scribed by Walle, U. K.


Book ID
126687838
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2002
Tongue
English
Weight
213 KB
Volume
30
Category
Article
ISSN
0090-9556

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Glucuronidation catalyzed by UDP-glucuronosyltransferase (UGT) enzymes is an important pathway in the metabolism of drugs as well as environmental chemicals. In this study, protein-protein interactions between human UGT2B7 and UGT1As and their effects on the enzymatic activities were investigated us