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Induction of Human UDP-glucuronosyltransferase 1A1 by Cortisol-GR

✍ Scribed by Toru Usui; Takuya Kuno; Takaharu Mizutani

Book ID
106469433
Publisher
Springer
Year
2006
Tongue
English
Weight
219 KB
Volume
33
Category
Article
ISSN
0301-4851

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Modulation of UDP-glucuronosyltransferas
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✍ Cornelia M. Smith; Stephanie R. Faucette; Hongbing Wang; Edward L. LeCluyse πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 477 KB

## Abstract The primary objective of this study was to evaluate the modulation of UGT1A1 expression in human hepatocytes using prototypical CYP450 inducers. A bank of 16 human livers was utilized to obtain an estimate of the range of UGT1A1 protein expression and catalytic activity. Concentration‐d