Stimulation of prostaglandin E and hualuronic acid production by rubella and measles viruses in human synovial fibroblast cultures
β Scribed by Michael Yaron; Ilana Yaron; Ophyra Smetana; Dan Caspi; Uriel Zor
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 94 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0004-3591
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The authors have shown that the interferon inducer, double-stranded polynucleotide, poly I poly C, and human interferon stimulate prostaglandin E (PGE) (1) and hyaluronic acid (HA) production (2) in human synovial fibroblast cultures and induce inflammation when injected into the rat joint ( 3 ) . A
## Abstract The interferonβinducer, polyinosinate. Polycyctidylate [Poly (I). Poly (C)] stimulated both prostaglandin E (PGE) and hyaluronic acid (HA) production by human cultured synovial fibroblasts. Increased accumulation of PGE in the medium was noted within 3 hours of culture, while accumulati
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