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Stimulation of procollagenase synthesis in human rheumatoid synovial fibroblasts by mononuclear cell factor/interleukin 1

✍ Scribed by Peter A. McCroskery; Sadachika Arai; Edward P. Amento; Stephen M. Krane


Book ID
115917259
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
618 KB
Volume
191
Category
Article
ISSN
0014-5793

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Monocyte/macrophage polypeptides (monokines) alter the properties of synovial cells. This interaction could explain some of the properties of the inflamed synovium in rheumatic disease. Only recently has it been possible to test the action of purified monokines on the target synovial cells. We repor