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Stimulation of melanogenesis in cultured melanoma cells by calciferols

โœ Scribed by Atsushi Oikawa; Michie Nakayasu

Book ID
115904301
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
312 KB
Volume
42
Category
Article
ISSN
0014-5793

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## Abstract A permanent cell line C~2~M of mouse melanoma B16 was highly melanized in a modified Eagle's MEM supplemented with 10% calf serum, when the medium contained 1 mM galactose and 10 mM pyruvate instead of 5.5 mM glucose. The activity of the key enzyme for melanogenesis, tyrosinase (EC 1.14