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Inhibitory effect by polyunsaturated fatty acids on melanogenesis in cultured human melanoma cells

โœ Scribed by Hashizume, R.; Doi, H.; Hirano, J.; Fukushima, S.; Kobayashi, N.; Mori, T.

Book ID
123233491
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
136 KB
Volume
4
Category
Article
ISSN
0923-1811

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## Abstract A permanent cell line C~2~M of mouse melanoma B16 was highly melanized in a modified Eagle's MEM supplemented with 10% calf serum, when the medium contained 1 mM galactose and 10 mM pyruvate instead of 5.5 mM glucose. The activity of the key enzyme for melanogenesis, tyrosinase (EC 1.14