Stimulation of human cellular thymidine kinase activity during abortive infection with herpes simplex virus type 2
β Scribed by Mario J. Marcon; Louis S. Kucera
- Book ID
- 119009868
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 311 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0042-6822
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## Abstract We investigated some of the biological and biochemical characteristics of a neurovasive, retinovirulent herpes simplex virus type 2 strain SL (HSVβ2[SL]) and compared them with those of a neurovirulent, nonretinovirulent HSVβ2(186). HSVβ2(SL) was shown to spread rapidly and produce larg
## Abstract Isozyme analyses have been carried out to investigate the sites of integration of the herpes simplex type 2 (HSVβ2) thymidine kinase (TK) gene in biochemically transformed human [HeLa(BU25)/HSVβ2β6 Cl 4] cells. Extracts were prepared from He La (BU25)/HSVβ2β6 Cl 4 cells and from humanβm