## Abstract We previously isolated an acyclovir (ACV)‐resistant herpes simplex virus type 1 (HSV‐1), strain TAR, from a child with Wiskott‐Aldrich syndrome. An acyclovir‐sensitive HSV‐1, strain TAS, had been isolated from the same patient before the isolation of HSV‐1 TAR. The TK protein of ACV‐sen
Effect of acyclovir and presence of cellular and viral thymidine kinase activity in herpes simplex virus infected cells
✍ Scribed by J. Harmenberg; C. F. R. Källander; J. S. Gronowitz
- Publisher
- Springer Vienna
- Year
- 1982
- Tongue
- English
- Weight
- 417 KB
- Volume
- 74
- Category
- Article
- ISSN
- 1432-8798
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## Abstract We investigated some of the biological and biochemical characteristics of a neurovasive, retinovirulent herpes simplex virus type 2 strain SL (HSV‐2[SL]) and compared them with those of a neurovirulent, nonretinovirulent HSV‐2(186). HSV‐2(SL) was shown to spread rapidly and produce larg
Recurrent acyclovir (ACV)-resistant (ACV-r) herpes simplex virus type 1 (HSV-1) infections occurred in a patient with Wiskott-Aldrich syndrome, an X-linked recessive immunodeficiency syndrome composed of three clinical characteristics of immunodeficiency, thrombocytopenia, and an eczematous dermatit