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Stimulation of Division of Sparse and Confluent 3T3 Cell Populations by a Fibroblast Growth Factor, Dexamethasone, and Insulin

โœ Scribed by Denis Gospodarowicz and John S. Moran

Book ID
123652957
Publisher
National Academy of Sciences
Year
1974
Tongue
English
Weight
797 KB
Volume
71
Category
Article
ISSN
0027-8424

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โœ Steven P. Rose; Rebecca M. Pruss; Harvey R. Herschman ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 409 KB

Epidermal Growth Factor (EGF) at concentrations of 10(-9) to 10(-10) M initiates cell division in both confluent and low density non-dividing 3T3 cells. Four days after addition of EGF to confluent or low density non-dividing 3T3 cells there is a 2- and 5-fold increase, respectively, in cell number.