✦ LIBER ✦

Initiation of 3T3 fibroblast cell division by epidermal growth factor

✍ Scribed by Steven P. Rose; Rebecca M. Pruss; Harvey R. Herschman

Publisher: John Wiley and Sons
Year: 1975
Tongue: English
Weight: 409 KB
Volume: 86
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1040860504

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✦ Synopsis

Epidermal Growth Factor (EGF) at concentrations of 10(-9) to 10(-10) M initiates cell division in both confluent and low density non-dividing 3T3 cells. Four days after addition of EGF to confluent or low density non-dividing 3T3 cells there is a 2- and 5-fold increase, respectively, in cell number.

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