Colchicine enhances the effect of growth factors on the initiation of DNA synthesis in sparse and confluent Swiss 3T3 cells
β Scribed by OTTO, A; ULRICH, M; DEASUA, L
- Book ID
- 122314098
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 493 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0309-1651
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## Abstract Quiescent Swiss mouse 3T3 cells react to a heat treatment at 46Β°C for 20 min by changing their flat, wellβextended morphology to a round appearance with retracted cytoplasmic processes during the subsequent 2 h at 37Β°C. The percentage of morphologically changed cells was used to quantif
Epidermal growth factor (EGF) stimulates the initiation of DNA synthesis in Swiss 3T3 cells after a constant prereplicative period of 14-15 hours. The final rate of initiation follows apparent first-order kinetics and can thus be quantified by a rate constant k. The value of k can be changed by late