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STI 571 active in patients with rare GI cancer

โœ Scribed by Innes, Carmen

Book ID
120865976
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2001
Weight
148 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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## Abstract STI571, or imatinib, selectively inhibits BCR/ABL, PDGFR and cโ€kit kinase activity. It has been reported that a large proportion of small cell lung cancer (SCLC) cell lines and tumors express cโ€kit and that STI571 inhibits tumor cell growth. We therefore investigated the therapeutic eff