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Follow-up Study of Patients Diagnosed with Chronic Myelogenous Leukemia Treated with STI 571 in Ecuador

✍ Scribed by César Paz-y-Miño; Melissa Arévalo; María Eugenia Sánchez; Claudio Cañizares; Paola E. Leone


Book ID
113467054
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
63 KB
Volume
38
Category
Article
ISSN
0188-4409

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## Abstract Chronic myelogenous leukemia is caused by the acquisition of the reciprocal (9;22)(q34;q11) chromosomal translocation in hematopoietic stem cells. The fusion protein showed higher and aberrant tyrosine kinase activity. The inhibition of the tyrosine kinase activity of the protein repres