Sterol biosynthesis in Saccharomyces fermentati

✍ Scribed by A. H. El-Refai; I. A. El-Kady

• Book ID: 102388240
• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 332 KB
• Volume: 8
• Category: Article
• ISSN: 0233-111X
• DOI: 10.1002/jobm.19680080504

✦ Synopsis

The effect of the nature and concentration of carbon and nitrogen sources were considered by many investigators t o be among the decisive factors influencing the biosynthesis of sterols in yeast. Therefore, DULANEY et al. (1954) studied the effect of different carbon sources on sterol formation in Saccharomyces cerevisiae and found that maltose was the superior carbon source for growth and ergosterol production. Using either the same species (Sacch. cerevisiae or Sacch. curlsbergensis) GAL'TSOVA and VAKINA (1959) noted that the optimal carbon Sources for the accumulation of ergosterol are glucose, sucrose and pyruvic acid. Furthermore, STARR and PARKS (1962) observed that a wild type of Sacch. cerevisiae could utilize maltose, glucose, sodium acetate and ethanol as carbon sources. They reported that in aerobic resting cultures the ergosterol synthesis was stimulated only by glucose and ethanol. Under these conditions the synthesis of sterol was proportional t o the amount of glucose provided.