In Saccharomyces cerevisiae, the products of eleven different genes are needed for a functional sulfate assimilation pathway. Only five enzymatic steps are known in this pathway. The study of the gene-enzyme relationships has shown that the enzymes catalysing two of these steps are probably heteropo
β¦ LIBER β¦
Methionine biosynthesis in Saccharomyces cerevisiae
β Scribed by Masselot, Monique ;de Robichon-Szulmajster, Huguette
- Book ID
- 104691393
- Publisher
- Springer
- Year
- 1975
- Tongue
- English
- Weight
- 536 KB
- Volume
- 139
- Category
- Article
- ISSN
- 0026-8925
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β¦ Synopsis
In order to analyse how many structural genes are implicated in the specific steps of the biosynthesis of methionine in Sacch. cerevisiae, a hundred mutants were studied by complementation. 21 groups were defined named MET1 to MET25. Neither recombination between independent mutants of the same complementation group nor linkage between different groups was found. Preliminary to biochemical studies, mutants of each complementation group were tested for their capacity to utilize various precursors of methionine.
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