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Methionine biosynthesis in Saccharomyces cerevisiae

✍ Scribed by Masselot, Monique ;de Robichon-Szulmajster, Huguette


Book ID
104691393
Publisher
Springer
Year
1975
Tongue
English
Weight
536 KB
Volume
139
Category
Article
ISSN
0026-8925

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✦ Synopsis


In order to analyse how many structural genes are implicated in the specific steps of the biosynthesis of methionine in Sacch. cerevisiae, a hundred mutants were studied by complementation. 21 groups were defined named MET1 to MET25. Neither recombination between independent mutants of the same complementation group nor linkage between different groups was found. Preliminary to biochemical studies, mutants of each complementation group were tested for their capacity to utilize various precursors of methionine.


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