The title compound, C 11 H 12 O 4 , was prepared from the Knoevenagel condensation reaction of 3,4-dihydroxybenzaldehyde and monoethyl malonate. The almost planar molecule is the E isomer.
Steroids. XIX. 3-phenyl - and 3-ethyl-4-azacholestanes
✍ Scribed by Norman J. Doorenbos; Kenneth A. Kerridge
- Book ID
- 112121298
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1965
- Tongue
- English
- Weight
- 340 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0022-152X
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📜 SIMILAR VOLUMES
Single-crystal X-ray study T = 250 K Mean '(C±C) = 0.004 A Ê R factor = 0.056 wR factor = 0.156 Data-to-parameter ratio = 15.2 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.
## Recently, Fischer (1) described the phetotochtical ## OOMerSiOZ3 Of Fphenyl-lactam (I) into the ketone (II). Hoffba~ (2) and YII~~ (3)
The crystal structure of the title compound, C 20 H 20 N 2 O 4 , contains two molecules in the asymmetric unit. The crystal packing involves -, C-HÁ Á ÁO and C-HÁ Á ÁN interactions.
In the crystal structure of the title compound, C 15 H 14 N 4 , all three aromatic rings, viz. 1,2,4-triazole, pyridine and benzene. The crystal structure shows that all three rings are not coplanar.
The title compound, C 22 H 30 O 4 , is known as a chemopreventive agent against colon tumor development. The molecular structure is nearly planar, showing a trans arrangement with respect to the C C bond of the phenylpropenoate moiety.