Ethyl 3-[4-(ethoxycarbonyl)phenyl]-3,4-dihydroquinazoline-6-carboxylate
✍ Scribed by Bhuiyan, M. Delower H. ;Clegg, Jack K. ;Try, Andrew C.
- Publisher
- International Union of Crystallography
- Year
- 2006
- Tongue
- English
- Weight
- 307 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1600-5368
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✦ Synopsis
The crystal structure of the title compound, C 20 H 20 N 2 O 4 , contains two molecules in the asymmetric unit. The crystal packing involves -, C-HÁ Á ÁO and C-HÁ Á ÁN interactions.
📜 SIMILAR VOLUMES
Single-crystal X-ray study T = 294 K Mean (C-C) = 0.004 A Disorder in main residue R factor = 0.051 wR factor = 0.149 Data-to-parameter ratio = 12.7 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.
The title compound, C 18 H 18 N 2 O 5 , was synthesized from 2,3dimethoxyphenylmethylidenemalononitrile and ethyl acetoacetate in the presence of triethylbenzylammonium chloride in an aqueous medium. The pyridone and benzene rings make a dihedral angle of 63.8 (1) . There are intermolecular C-HÁ Á Á
ÁC 4 H 8 O 2 , the dihydropyridine rings display envelope configuration. The solvent molecule links to the anhydride via weak C-HÁ Á ÁO hydrogen bonding.
The title compound, C 23 H 21 NO 4 , was synthesized by the reaction of 1-naphthol with ethyl cyanocaetate and 4methoxybenzaldehyde in ethanol under microwave irradiation. In the structure of C 23 H 21 NO 4 , there are intramolecular and intermolecular N-HÁ Á ÁO hydrogen bonds, also C-HÁ Á Á interac