DFT calculations at the Becke3LYP/6-31G\* level were employed to demonstrate that the pinacol rearrangement of ethylene glycol and the 1,1-dimethyl and 1,1,2-trimethyl analogs undergo pinacol rearrangements by a concerted hydrogen-bridged transition structure. No evidence for a bridged intermediate
โฆ LIBER โฆ
Stereospecificity of Hydrogen Migration in the Pinacol Rearrangement
โ Scribed by Mislow, Kurt; Siegel, Maurice
- Book ID
- 126023083
- Publisher
- American Chemical Society
- Year
- 1952
- Tongue
- English
- Weight
- 288 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0002-7863
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## swnmary: Completely stereospecific 1,2-migration of alkyl groups was achieved in Et2AlCL- prowted pinacoZ-type rearrangement of chiral B-mesyZoxy alcohols to give optically pure aalkyl ketones including both enantiomers of 4-methyl-3-hexanone, an alarm pheromone of ant.
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