Stereospecific Synthesis of Cryptophycin 1
β Scribed by Li, Lian-Hai; Tius, Marcus A.
- Book ID
- 126968162
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 67 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1523-7060
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π SIMILAR VOLUMES
AbstractΓA total synthesis of cryptophycin 337 (1-aza-cryptophycin 1, 2), an analogue of the potent antitumor antibiotic cryptophycin 1 (1), is described. Cryptophycin 337 was unstable and underwent an unexpected skeletal rearrangement. (R)-Mandelic acid was used as the sole source of asymmetry for
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