𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Stereospecific synthesis of (+) -cahbocyclic 2'-deoxyadenosine. an improved procedure for the preparation of (+)-(1r,2s,4r)-4-amino-2-hydroxy-1-hydroxymethylcyclopentane.

✍ Scribed by J. Be´res; Gy. Sa´gi; E. Baitz-Ga´cs; I. Töaöaközi; L. ötivös

Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
567 KB
Volume
44
Category
Article
ISSN
0040-4020

No coin nor oath required. For personal study only.

✦ Synopsis

An improved procedure for the preparation of a versatile synthetic precursor, (+)-~, of carba-2'-deoxyribonucleosides and the first stereospecific way to enantiomerically pure carbocyclic 2 '-deoxyadenosine , (+)-li, are presented from bicyclic lactone diol (+)-1. An unexpected formation of the disubstituted 2-oxabicyclo[2.2.1)heptane skeleton ~ through a hypervalent iodo species derived from ~ is also reported.

📜 SIMILAR VOLUMES

An improved synthesis of (2S, 4S)- and (
An improved synthesis of (2S, 4S)- and (2S, 4R)-2-amino-4-methyldecanoic acids: assignment of the stereochemistry of culicinins
✍ Wei Zhang; Ning Ding; Yingxia Li 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 205 KB

## Abstract An improved synthesis of (2__S__, 4__S__)‐ and (2__S__, 4__R__)‐2‐amino‐4‐methyldecanoic acids was accomplished using a glutamate derivative as starting material and Evans' asymmetric alkylation as the decisive step. The NMR data of the two diastereomers were measured and compared with

ChemInform Abstract: An Asymmetric Synth
ChemInform Abstract: An Asymmetric Synthesis of (1S,4R)-4-Amino-2-cyclopentenol Derivatives.
✍ Masatoshi Asami; Megumi Ogawa; Seiichi Inoue 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 27 KB 👁 2 views

An Asymmetric Synthesis of (1S,4R)-4-Amino-2-cyclopentenol Derivatives. -Chiral cyclopentenols (II), prepared from mesocyclopentene oxide (I) under optimized conditions, are easily transformed to the title compounds (III) (useful chiral synthons) by oxidation. -(ASAMI,

Studies on the synthesis of biphenylneol
Studies on the synthesis of biphenylneolignans. Part 1: Enantioselective synthesis of (S,S)- and (R,R)-2,2′-dimethoxy-4-(3-hydroxy-1-propenyl)-4′-(1,2,3-trihydroxypropyl)diphenyl ether
✍ Yi Yang; Chenglu Zhang; Guoren Yue; Pingyan Bie; Xinfu Pan 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 129 KB

Two erythro-isomers of 2,2%-dimethoxy-4-(3-hydroxy-1-propenyl)-4%-(1,2,3-trihydroxypropyl)diphenyl ether, (7%S, 8%S)-9 and (7%R, 8%R)-9, were synthesized in seven steps, in which an improved method for the synthesis of the key intermediate 3 was developed. The absolute configuration of the target mo