𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Stereospecific isomerization of 3-substituted-3-bromo-1,2-epoxypropanes using magnesium bromide

✍ Scribed by Michinori Karikomi; Takeshi Takayama; Kazuo Haga

Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
118 KB
Volume
43
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

A novel stereospecific isomerization reaction of 3-substituted-3-bromo-1,2-epoxypropane derivatives into 1-substituted-3-bromo-1,2-epoxypropane derivatives is described. The choice of the solvent crucially influences the isomerization. The tendency of this isomerization could be predicted by comparison of the free energies calculation using ab initio and DFT methods.

📜 SIMILAR VOLUMES

Reaction of 3-substituted and 4-bromo-3-
Reaction of 3-substituted and 4-bromo-3-substituted isoquinolin-1-(2h)-ones with propargyl bromide
✍ Cyril Odianose Usifoh 📂 Article 📅 2001 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 39 KB

## Abstract Isoquinolinones were brominated using __N__‐bromosuccinimide in dimethylformamide at room temperature to give 4‐bromo‐3‐substituted isoquinolin‐1‐(2__H__)‐ones. The reaction of these isoquinolinones with propargyl bromide in the presence of anhydrous potassium carbonate yielded __N__ an

The synthesis of 14C -3- chloro -, 3 - b
The synthesis of 14C -3- chloro -, 3 - bromo - and 3 - iodo -propan - 1, 2 - diol and 2, 3 - epoxypropan - 1 -01
✍ A. R. Jones 📂 Article 📅 1973 🏛 John Wiley and Sons 🌐 French ⚖ 163 KB 👁 1 views

## Abstract A convenient procedure has been developed for the synthesis of ^14^C‐3‐chloropropan‐1, 2‐diol (α‐chlorohydrin, **I**) from ^14^C‐glycerol which can also be applied to the preparation of ^14^C‐3‐bromopropan‐1, 2‐diol (α‐bromohydrin, **III**). These two compounds can be converted, respect